MTX monotherapy (MTG) is recommended as (part of) first choice treatment but no head-to-head comparisons are available comparing MTX–HCQ CTG with MTG. RA patients from the Sint Maartenskliniek and Radboudumc Nijmegen who started MTX with or without concomitant HCQ from April 2010 to October 2015 were included. What are the side affects of hydroxychloroquine Plaquenil causes lowcalcium levels Plaquenil and cymbalta Plaquenil hydroxychloroquine and Rheumatrex and Trexall methotrexate are used to treat rheumatoid arthritis. Plaquenil is also used to treat or prevent malaria, and to treat symptoms of discoid or systemic lupus erythematosus. Rheumatrex and Trexall are also used to treat some cancers and severe skin diseases such as severe psoriasis. Sorry to hear that you are having a lot of pain with your RA. I have lupus which mainly affects my joints and skin. I have been taking hydroxychloroquine which is the generic of plaquenil for the past three years. My rheumy recently added Imuran instead of methotrexate. Plaquenil hydroxychloroquine takes up to 3 months to begin working. Plaquenil hydroxychloroquine has been shown to improve physical function in up to 80% of patients with rheumatoid arthritis. Plaquenil hydroxychloroquine is commonly used for lupus in children because of less side effects compared to other medications. Plaquenil hydroxychloroquine helps minimize joint damage. Regression modelling was used to correct for confounding. The primary outcome was the between-group ΔDAS28-CRP at 6 months, and secondary outcomes were ΔDAS28-CRP at 12 months, EULAR response at 6 and 12 months, and treatment intensification. Plaquenil vs methotrexate for ra Methotrexate vs Plaquenil? -, Arthritis Which would you pick and why? - Plaquenil or. Chloroquine phosphate for aquarium Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Methotrexate vs Plaquenil Comparison -. Compare Plaquenil vs Methotrexate -. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. According to the American College of Rheumatology, hydroxychloroquine Plaquenil, is a “disease-modifying anti-rheumatic drug DMARD,” meaning that it helps reduce the pain and swelling that come with arthritis. It can also reduce the incidence of joint damage. I started out on the Plaquenil and Methotrexate oral and while my RA symptoms were reduced some, the methotrexate made me extremely ill for 2 days after I took each dose. The doctor then kept me on my plaquenil and added Leflunomide Arava to replace the methotrexate. January 2, 2013. One Chick is looking for your advice on medication My Rheumatologist recommended Methotrexate for my RA which I haven’t started taking yet because I was waiting until after the holidays in case I have side effectshowever she mentioned Plaquenil but she felt the Methotrexate is better for my RA.