It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine hair lightening Hydroxychloroquine image Can you overdose on plaquenil These findings will be particularly evident in the parafoveal area. 6 SD-OCT parafoveal defects associated with Plaquenil toxicity have been described as a “flying saucer sign” and/or “sinkhole displacement.” 7 Plaquenil maculopathy is an uncommon side effect of the systemic medication, Hydroxychrloroquine. This lecture will guide the optometrist in diagnosis and management of Plaquenil maculopathy. The course will review updated guidelines from the American Academy of Ophthalmology and discuss exciting new research utilizing OCT. None of the primary medical indications for hydroxychloroquine therapy were significantly associated with an increased prevalence of retinal toxicity. A multivariable logistic regression analysis was performed Table 1 on those factors that showed significant differences by univariate analysis, along with age which has been postulated to increase risk. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil flying saucer How to Succeed in Plaquenil Screenings, Pacific University College of Optometry Plaquenil toxicity continuing educationHydroxychloroquine allergyPlaquenil kidney damageZydus hydroxychloroquine gluten Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions.. Toxic Retinopathy With Hydroxychloroquine Therapy - JAMA. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to presentation. Past Ocular History None Medical History Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Flying saucer sign in the right eye, showing loss of the perifoveal ellipsoid line and thinning of the external nuclear layer. Autofluorescence was also performed in both eyes, revealing bull's-eye maculopathy which indicates severe retinal damage Fig. 3. The “flying saucer” sign was present in all three of the five patients who presented with early HCQ retinopathy. Two patients presented with advanced HCQ retinopathy and moderate to severe vision loss.