Common manifestations may include arthralgias and arthritis, Raynaud syndrome, malar and other rashes, pleuritis or pericarditis, renal or central nervous system involvement, and hematologic cytopenias. Diagnosis requires clinical and serologic criteria. Treatment of severe, ongoing, active disease requires corticosteroids and immunosuppressants. Plaquenil arthritis medicine Hydroxychloroquine nclex Chloroquine clinical trials cancer Hydroxychloroquine allergic reaction Systemic lupus erythematosus SLE, is the most common type of lupus. SLE is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. Chronic cutaneous lupus erythematosus. Chronic cutaneous LE accounts for 80% of presentations with cutaneous LE. About 25% of patients with chronic cutaneous LE also have systemic LE. Discoid LE. Discoid LE is the most common form of chronic cutaneous LE. INTRODUCTION Hydroxychloroquine HCQ is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus SLE. Systemic lupus erythematosus (SLE) is more common among blacks and Asians than whites. Of all cases, 70 to 90% occur in women (usually of child-bearing age). Chronic lupus erythematosus plaquenil Discoid lupus erythematosus - Wikipedia, Cutaneous lupus erythematosus DermNet NZ Chloroquine resistance malaria cdcHydroxychloroquine 400 mg cost Lupus-- also known as systemic lupus erythematosus -- is a disease of the immune system. Normally, the immune system protects the body from infection. In lupus, however, the immune system. Lupus Causes, Risk Factors, Symptoms, Complications.. Hydroxychloroquine in systemic lupus erythematosus SLE.. Systemic Lupus Erythematosus. Chronic cutaneous lupus erythematosus CCLE most commonly presents in the form of discoid lupus erythematosus DLE with pink-to-violaceous coin-shaped plaques with hyperkeratosis and follicular plugging that heal with atrophy, scarring, hyperpigmentation, and telangiectasias. Hydroxychloroquine is used to treat discoid lupus erythematosus DLE or systemic lupus erythematosus SLE or lupus. It is also used to treat acute and chronic rheumatoid arthritis. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms Tablet; Before Using Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases.