Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. What blood tests are required while on plaquenil Hydroxychloroquine weight loss Clarithromycin and hydroxychloroquine lyme Most of the patients described were African or of African descent with dark skin who had been exposed to the sun. One was a Hispanic patient who developed vitiligo-like skin depigmentation after 1 month of chloroquine therapy for cutaneous lupus erythematosus. The skin rapidly repigmented after discontinuation of chloroquine therapy. Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Chloroquine is metabolized in the liver, primarily by CYP2C8 and CYP3A4 enzymes, and it can selectively inhibit CYP2D6 activity. Drugs that inhibit CYP3A4 such as ritonavir may increase plasma levels of chloroquine. Potential interactions may also exist between chloroquine and drugs that are substrates for CYP2D6. 11,16,17 Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Facts on chloroquine Chloroquine Uses, Side Effects & Warnings -, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Plaquenil and sun sensitivityPlaquenil goodrxChloroquine cryptocaryonChloroquine tablets side effectsGeneric for hydroxychloroquine 200 mg Summary. Aralen is the brand name for the generic drug chloroquine, an anti-malaria drug used to treat malaria and amebiasis infection that's spread outside of the intestines. Dosage, drug interactions, and pregnancy and breastfeeding safety information should be reviewed prior to taking this drug. Aralen chloroquine Malaria Drug Side Effects & Dosage. Chloroquine Information for Providers AIDSinfo. Chloroquine drug Britannica. Each tablet contains 500 mg of Chloroquine phosphate USP, equivalent to 300 mg Chloroquine base. Inactive Ingredients colloidal silicon dioxide, dibasic calcium phosphate, hydroxypropylmethylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate80, pregelatinized starch. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Chloroquine enters the red blood cell, inhibiting the parasite cell and digestive vacuole by simple diffusion. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion.