It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Chloroquin urine color Chloroquine phosphate and leather coral Systemic disease Kidney or liver dysfunction Ocular disease Retinal disease or maculopathy Marmor MF, Kellner U, Lai T, et al. Revised Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy. Opthalmology. 2011;18 2 415-422. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1is now considered for new disease applications in diabetes, heart disease and adjunct. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Plaquenil liver kidney toxicity Plaquenil Hydroxychloroquine - Side Effects, Dosage., Hydroxychloroquine Plaquenil Toxicity and. I don't like plaquenilPlaquenil blurry vision years after stoppingDoes chloroquine sulfate have sulfa in itHydroxychloroquine bluelight Removing waste products and toxic substances; Regulating the hormones chemical messengers that help control blood pressure and blood volume; Lupus Nephritis. Inflammation of the nephrons, the structures within the kidneys that filter the blood, is called glomerulonephritis, or nephritis. Plaquenil side effects - kidney problems? - Symptoms.. Taking Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine-Induced Retinal Toxicity - American.. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Age, liver disease, and genetic factors e.g. polymorphisms in the cytochrome P450 gene which may impact blood concentrations are thought to be lesser risk factors associated with toxicity risk. Kidney and liver disease predispose to hydroxychloroquine toxicity due to impaired clearance of the drug.