It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Desethyl hydroxychloroquine Hydroxychloroquine site mayoclinic.org I took Plaquenil 200 mg once/day for about a year and kept telling my rheumatologist I didn't think it was helping at all. My current rheumatologist I switched for a second opinion on everything and I discussed it and I said I don't think it's helping me at all. He said it seems to be because my j For treating lupus in adults, the recommended starting Plaquenil dosage is 400 mg once or twice a day. After a while, your healthcare provider may recommend a lower dosage such as 200 mg once daily. For the treatment of systemic lupus erythematosus, patients should take 200 mg to 400 mg of hydroxychloroquine per day as one dose or divided into two separate doses. 1, 2 The recommended hydroxychloroquine dosage for rheumatoid arthritis is 400 mg to 600 mg a day by mouth as a single dose or divided into two separate doses. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil 200 mg twice a day I am prescribed plaquenil I take the substitute., Taking Plaquenil for Various Conditions and Treatment Tips Chloroquine intercalatingCan plaquenil cause yeast infectionsChloroquine selleckchemIs hydroxychloroquine an anti inflammatory This type of medication has to be taken everyday at 200mg twice a day. According to my rheumy it does not help at a lower dose and you must take it everyday to work. Kota 11/18/2018 I've taken plaquenil for many years. Does anyone use Plaquenil ? DailyStrength. Hydroxychloroquine Plaquenil Success, Reviews and Side Effects. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Mg PO twice daily plus methotrexate 7.5 to 17.5 mg PO once weekly for 2 years led to an ACR20 in 60% of 58 patients with active disease and a disease duration of at least 6 months. Thirty-three of the 58 patients had an inadequate response to previous methotrexate monotherapy, and 25 patients were methotrexate naive. The dose for malaria prevention is 400 mg every week starting 1 or 2 weeks before exposure and for 4 weeks after leaving the high risk area. The recommended adult dose for rheumatoid arthritis is 400-600 mg daily for 4-12 weeks followed by 200-400 mg daily. Adult dosing ranges from 200 mg or 400 mg per day 6.5mg/kg. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet.