One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. How often to take aralen Chloroquine sp combination Plaquenil treat lupus Hydroxychloroquine sulfate usp 200 mg The quinine family of drugs has been used for a variety of conditions, and Hydroxychloroquine Sulphate Plaquenil is a valuable drug for the treatment of certain auto-immune collagen-vascular disease processes. Rheumatoid Arthritis RA and Systemic Lupus Erithematosus SLE are conditions for which Hydroxychloroquine has been found to be of help. Here is a look at the 2011 testing guidelines for patients on Plaquenil guidelines. Diana L. Shechtman, O. D. and Paul M. Karpecki, O. D. A 45-year-old black female presented with no ocular or visual complaints. Her ocular history was unremarkable. However, her medical history was significant for a recent diagnosis of lupus. Overall, around seven patients out of every 100 taking hydroxychloroquine for more than five years may develop retinopathy that can be detected with specialised tests. The risk is much higher in patients who have been taking the drug for 20 years or more. In these patients between 20 and 50 out of 100 will develop retinopathy. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Test for plaquenil retinopathy Hydroxychloroquine-Induced Retinal Toxicity - American., New Plaquenil Guidelines Chloroquine po 300 mg daily prophylaxisHydroxychloroquine plaquenil eksisozlukWhat is hydroxychloroquine sulfate tablets used to treat New research finds that measuring blood levels of the medication hydroxychloroquine Plaquenil in people with lupus may be an effective way to predict risk of retinopathy, a disease which results in impaired or complete loss of vision. The study assessed 537 people with lupus and measured the levels of the drug present in their blood. Study Finds Blood Levels of Plaquenil may be Important.. Hydroxychloroquine screening. Plaquenil Retinopathy Screening Requirements Are You Up to.. MfERG may be the most sensitive test for early HCQ retinopathy, and numerous studies have evaluated the use of mfERG in the screening of HCQ retinopathy.19,20 Unlike full-field ERG, mfERG can localize deficiencies to the central macula, thereby detecting the subtle changes characteristic of early HCQ retinopathy.21,22 Specifically, paracentral reductions in amplitude, indicative of depressed retinal function, are the most specific waveform pattern for HCQ retinopathy Fig. 7. Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test. Hydroxychloroquine is an antimalarial drug used to treat or prevent malaria. It is highly effective against erythrocytic forms of Plasmodium, but not effective against exoerythrocytic forms of parasites.