If they’re more severe or don’t go away, talk to your doctor or pharmacist. Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Plaquenil induced psoriasis Retinal changes with the use of hydroxychloroquine Plaquenil Interactions Explained. The following sections explain in detail the potentially negative interactions that can occur when Plaquenil is combined with any of the drugs listed above. Certain Beta Blockers. Plaquenil may increase the level of some but not all beta blockers in the blood, perhaps increasing the risk of side effects. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. To treat malaria Plaquenil is usually given for 3 days. Some of these medicines that may lead to Plaquenil drug interactions include Certain beta blockers, such as Bisoprolol Zebeta ® Metoprolol Lopressor ®, Toprol XL ® Propranolol Inderal ® Sotalol Betapace ® Timolol Blocadren ® Carvedilol Coreg ® However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. Serious side effects and their symptoms can include the following: Disclaimer: Our goal is to provide you with the most relevant and current information. Drug interaction plaquenil and doxycycline Doxycycline Contraindications, Drug & Food Interactions., Plaquenil Uses, Dosage & Side Effects - Plaquenil side effects fluid retention Doxycycline oral tablet is available as both a generic and brand-name drug. Brand names Acticlate, Doryx, Doryx MPC. Doxycycline comes in three oral forms a tablet, a capsule, and a suspension. It also comes as a solution for injection, which is only given by a healthcare provider. Doxycycline Side Effects, Dosage, Uses, and More. Plaquenil Interactions - Antibiotics Home Page. Doxycycline and plaquenil, doxycycline and plaquenil Pill.. This appendix provides a table of drug interactions with medications used in other conditions. The British National Formulary BNF includes a summary appendix dedicated to drug interactions. More detailed information can be found in Stockley's Drug Interactions Baxter, 2008. Both of these sources should be checked before adding new drugs to a prescription, particularly if 1 any of the. The tetracycline antibiotic doxycycline, in combination with hydroxychloroquine OHCQ, is recommended for the long-term treatment of Q fever endocarditis 18 months for native valves and 24 months for prosthetic valves 14, 15. Drug interactions that are of greatest concern are those that reduce the desired effects or increase the adverse effects of the drugs. Drugs that reduce the absorption or increase the metabolism or elimination of other drugs tend to reduce the effects of the other drugs.