I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Volume of distribution of chloroquine Chloroquine pretreatment degradation toxicity Plaquenil eye exam report How many people survived malaria with chloroquine A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects. Plaq and some of my other meds say they cause stomach upset and diarrhea, but not gas. I am also on Keflex for sinus infection and strep throat, could it be the Keflex? I was wondering if since the plaq has reduced a lot of my pain, that I am taking much fewer narcotics which cause constipation, if that is why the plaq is now giving me the runs, gurgling stomach, GAS, GAS, GAS. I've been suffering from constipation for about a year. My constipation is mostly due to lack of moisture in the colon, not due to the hardness of my stool. Before testing positive for Antinuclear Antibodies Direct for Sjogren's Syndrome SS-B, I thought my constipation was perhaps due to my diabetes. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Plaquenil cause constipation Plaquenil and Constipation - Reviews - Treato, Plaquenil side effects" Lupus Community - Support Group If allergiac to plaquenil when she i see reactionChloroquine molecular formula Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil Side Effects Common, Severe, Long Term -. Constipation and Sjogren's Syndrome - HealthBoards. Long-Term Side Effects of Plaquenil for Rheumatoid.. If your fecal incontinence is caused by diarrhea, you should avoid foods that make your symptoms worse, such as. alcoholic beverages. drinks and foods containing caffeine. dairy products such as milk, cheese, and ice cream. fatty and greasy foods. drinks and foods containing fructose. Plaquenil usually has the opposite effect initially ! It's best to use dietary changes rather than a laxative, although I don't know exactly what it is you are taking. Drink plenty, more roughage/fibre prune juice or prunes all the usual stuff, cut out white flour products. Hello all. Recently prescribed Plaquenil filled with a generic hydroxychloroquine for the joint swelling associated with Scleroderma. I have been previously diagnosed with Lactose Intolerance and seem to have an attack every time I take the Plaquenil.