Malaria is a serious but rare disease caused by bites from infected mosquitos. Now the drug is used to treat inflammatory diseases. Photopsia plaquenil toxicity Plaquenil dosage autoimmune thyroiditis Can plaquenil cause swelling of mouth New guidelines for hydroxychloroquine guidelines 2016 pubmed HYDROXYCHLOROQUINE is used to treat rheumatoid arthritis and systemic lupus is also used to treat malaria. The lowest GoodRx price for the most common version of generic Plaquenil is around $20.41, 88% off the average retail price of $177.73. Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. Plaquenil can cause serious eye problems, especially if taken at high doses or for longer than five years. Contact your doctor immediately if you experience vision changes, seizures, mood changes, pain in the arms, legs or back, fast heartbeat, worsening of skin problems, or changes in hair such as loss or color change while taking Plaquenil. Some diseases treated with Plaquenil include: Plaquenil lowers your immune system’s ability to cause inflammation. This type of disease occurs when the body's immune system attacks its own healthy tissue. Plaquenil skin issues Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Skin Discoloration and Plaquenil - Arthritis Information You use aralen for what Usually, a skin biopsy is used to diagnose forms of cutaneous lupus, and various medications are available for treatment, including steroid ointments, corticosteroids e.g. prednisone, and antimalarials e.g. Plaquenil. Chronic Cutaneous Lupus Erythematosus CCLE / Discoid Lupus Erythematosus DLE. Lupus-Specific Skin Disease and Skin Problems Johns Hopkins.. Plaquenil Hydroxychloroquine MyLupusTeam. Plaquenil Reviews Everyday Health. Hydroxychloroquine Plaquenil stimulates the pigment producing cells in the skin called melanocytes. As a result, there is both hemosiderin iron and melanin accumulation in the dermis. The exact reasons why this phenomenon happens is not clear. However, trauma and bruising may faciliate the developement of pigmentation. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Aug 29, 2014 As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy.