Chloroquine malaria in wwii

Discussion in 'Generic & Brand Canadian Pharmacy' started by ESP, 20-Mar-2020.

  1. leopoldl Well-Known Member

    Chloroquine malaria in wwii


    Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. ovale, and P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Chloroquine isn’t new. Its use dates back to World War II, and it’s derived from the bark of the Chinchona tree, like quinine, a centuries-old antimalarial.

    Chloroquine is also used to treat amebiasis (infection caused by amoebae). Chloroquine is used to treat and to prevent malaria.

    Chloroquine malaria in wwii

    Malaria in Wars and Victims – Malaria Site, Treating Lupus with Anti-Malarial Drugs Johns Hopkins.

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  6. The United States Army and malaria control in World War II. Some of the major new tools which came out of this research were DDT and drugs such as Atabrine and chloroquine. The availability of Atabrine and DDT revolutionized malaria control throughout the world. The knowledge and experience gained through the use of these new tools by the.

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    Both adults and children should take one dose of chloroquine per week starting at least 1 week before. traveling to the area where malaria transmission occurs. They should take one dose per week while there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base 500mg salt. The Allied push to synthesize antimalarial agents during World War II was prompted by Japan's seizure of Java in 1942. At the time, 90% of the world's quinine came from Java. Allied interest in chloroquine followed the capture of German supplies of an analogue called sontoquine in Tunis in 1943. Anti-malaria drug being tested for efficacy against COVID-19 The trials show that the drug helps patients with fever, improves lung function and recovery time.

     
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  8. anzhela Well-Known Member

    Characterisation and solubility studies of Quinine sulphate. Hydroxychloroquine sulphate C 18 H 26 ClN 3 O. H 2 SO 4 is a synthetic quinine derivative commonly used as chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. It is sparingly soluble in water and insoluble in organic solvents such as chloroform,ether etc.

    Hydroxychloroquine sulfate ≥98% HPLC, powder Sigma-Aldrich