Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). Keyhole hydroxychloroquine Plaquenil sore throat Plaquenil or hydroxychloroquine HCQ is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid The Risk of Retinal Toxicity with Plaquenil YOUR CREDIBLE SJÖGREN'S RESOURCE Conclusions We identified HCQ in toxicity 1.7 % and bull's eye lesions in 0.7%.92.3% of patients are in high or very high-risk categories. Risk categories appeared to be weakly related to observed toxicity. There was no relation between risk categories and screening examination frequency. Hydroxychloroquine comes with risks if you don’t take it as prescribed. For malaria prevention Start this medication 1–2 weeks before traveling to a country where malaria is present. It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. Hydroxychloroquine eye exam frequency Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs, Hydroxychloroquine HCQ Eye Examination Frequency. Hydroxychloroquine and blood sugarOrder aralen 500mgPlaquenil scalp Of course the aim is avoid drug related retinal toxicity, which on ophthalmic examination, appears as the classic Bull’s eye change affecting the macula. Once retinal toxicity from hydroxychloroquine occurs, it is thought that the retinal changes are permanent and the disease can progress even if hydroxychloroquine is stopped for 1 to 3 years. My Take on New Ocular Screening Guidelines for Plaquenil.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine toxicity - EyeWiki. A 26-year-old black female presented in office for her annual comprehensive eye exam. Her medical history was significant for Plaquenil therapy spanning 12 years with a daily dose of 200mg twice daily. She presented with a best-corrected visual acuity of 20/20 OD and 20/20 OS. All preliminary testing revealed normal findings. Screening interval has also been updated. All patients will need a baseline screening before or within 1 year of initiation of hydroxychloroquine. The baseline examination includes a fundus examination. SD-OCT and visual field testing are added to the initial examination if a concurrent maculopathy is present. Plaquenil Eye Exams Plaquenil, also known as hydroxychloroquine, is a medication used in the treatment or prevention of malaria. It has also been used to treat other conditions, such as liver disease, that may have been caused by the same parasites that cause malaria.