Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine instructions Visual field changes with plaquenil Can plaquenil cause bruising Injection dose of chloroquine Cyclosporine was stopped and hydroxychloroquine 400 mg/day introduced. After a few weeks the SCLE lesions improved and so did arthralgia and psoriatic lesions, which became less inflamed and reduced in size. One month later, hydroxychloroquine was reduced to 200 mg/day, methotrexate was stopped and prednisone reduced to 5 mg/day. Nov 14, 2017. Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment. The study is based on hydroxychloroquine sulfate and methotrexate sodium the active ingredients of Plaquenil and Methotrexate, respectively. Other drugs that have the same active ingredients e.g. generic drugs or brand names are also considered. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Methotrexate trexall and hydroxychloroquine plaquenil Plaquenil hydroxychloroquine sulfate dose, indications., How Does Plaquenil Work For Rheumatoid Arthritis Can plaquenil be taking with trintellix Compare Hydroxychloroquine vs. Methotrexate, which is better for uses like RA, Lupus and Arthritis. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Compare Hydroxychloroquine vs Methotrexate - Comprehensive.. Plaquenil vs. Methotrexate side effect and effectiveness.. Effects of methotrexate and hydroxychloroquine combination.. Was the plaquenil controlling your RA symptoms? The trouble is you lose hair on Methotrexate too. But after losing heaps when I first went on it, I have stabalised now, I have thinner hair but it still looks fine and healthy. If plaq was working for your symptoms I'd go back on it. If you feel like the RA is escallating then go for mtx. Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and. Methotrexate vs plaquenil side effects long term and short term The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. But the Dr suggested I try Methotrexate instead.