This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Plaquenil causing psoriasis Malaria treatment chloroquine how many daily Plaquenil positive reviews Fluoroquinolones Their Connection to Older Anti-Malarial Drugs Even though I knew this information already and had posted on it briefly in a few forums I wanted to document the information that links fluoroquinolones with the older anti-malarial drugs that were known to be very toxic. Usual Adult Dose for Malaria Prophylaxis. 500 mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. How to admin chloroquine Chloroquine - Wikipedia, Chloroquine Dosage Guide with Precautions - Neutrophils plaquenilMethotrexate and plaquenil treatmentPlaquenil toxicity signs and symptoms A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Chloroquine Indications, Side Effects, Warnings -. Chloroquine C18H26ClN3 - PubChem. Aralen chloroquine Malaria Drug Side Effects & Dosage. Chloroquine is an anti-malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Good info, although the first article from 1989 doesn't appear to be about Chloroquine. The second article is partially about Chloroquine, and the third by NCBI from 15 years ago looks accurate, but based on one case study who was injected with Malaria. There are potential dangerous side effects to almost every medication on the planet. To prevent malaria, take chloroquine once weekly on the same day each week, or as directed by your doctor. Start this medication usually 1 to 2 weeks before you enter the malarious area, continue.