Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine diabetes Plaquenil naisea Bull's eye maculopathy hydroxychloroquine Chloroquine phosphate cas Although prednisone rarely has a direct interaction with other medications, there is an increased risk of infection when combining prednisone with other medications that affect your immune system. Additionally, when taking prednisone with NSAIDs such as naproxen or ibuprofen, there can be an increased risk of stomach ulcers. Plaquenil hydroxychloroquine and prednisone are used to treat symptoms of rheumatoid arthritis. Plaquenil is also used to treat or prevent malaria, and to treat symptoms of discoid or systemic lupus erythematosus. Prednisone is also used to treat or manage many conditions. Severe Interactions These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in formation. These medications may interact and cause very harmful effects. Consult your healthcare professional e.g. doctor or pharmacist for more in formation. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Prednisone and hydroxychloroquine interaction Side Effects of Prednisone Prednisone Tablets, USP., Plaquenil vs. Prednisone Prescription Treatment for. Hydroxychloroquine dogbonePlaquenil toxicity in macular oct layer changesPlaquenil long term side effects If you take medications such as estrogens or barbiturates with prednisone, drug interactions may potentially occur. These interactions can increase your risk of side effects, affect the level of prednisone in your blood, or decrease the effectiveness of some medications. Prednisone Drug Interactions - eMedTV Health Information.. Plaquenil Oral Interactions with Other Medication. Prednisone and Plaquenil DailyStrength. The prednisone began workiing in 3 days and helped reduce my joint inflammation. I had some issues with the plaquenil, nausea and extremity swelling. My rheumy told me that he has never had anyone have leg and hand swelling on plaquenil but he does not doubt it is from the plaquenil. When combined with alcohol, it is possible that certain side effects or risks of either prednisone or alcohol abuse are worsened. The Risks And Dangers Of Combining Alcohol And Prednisone. Both prednisone use and alcohol abuse have been linked to an increased risk of certain health problems. Prednisone may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent. In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you.