It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Hydroxychloroquine radiotherapy Plaquenil package insert SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. To the Editor Hydroxychloroquine HCQ is a well-established drug used in the treatment of systemic lupus erythematosus SLE. Lupus UK, a national registered charity supporting people who have SLE, has received a number of recent reports from patients who are experiencing new adverse effects from HCQ after being established on the treatment without any initial adverse effects. These reports. Unsteadiness, trembling, or other problems with muscle control or coordination vomiting Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Precautions The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Gi problems with hydroxychloroquine Effectiveness of Chloroquine and Hydroxychloroquine in., Increased Incidence of Gastrointestinal Side Effects in. Plaquenil and weight lossGrapefruit and plaquenilChloroquine mechanism malariaPlaquenil scalpAralen ranger apprentice Hydroxychloroquine for Crohns Disease and Ulcerative Colitis. Leonard B. Weinstock, M. D. Many anti-inflammatory medications used for rheumatoid arthritis have been applied to inflammatory bowel disease IBD therapy. Hydroxychloroquine for Crohns Disease and Ulcerative Colitis.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. Hydroxychloroquine can cause an upset tum, it's a common side effect so it could be the longer you're taking it there's a build up effect. Trouble is you've other things coming up so it could be nervous tum, or even the two both making your tum particularly sensitive. If any severe blood disorder such as aplastic anemia, agranulocytosis, leukopenia, or thrombocytopenia, appears which is not attributable to the disease under treatment, consider discontinuation of hydroxychloroquine sulfate. Hydroxychloroquine sulfate should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6.