One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil pronounciation Patient information leaflet on hydroxychloroquine Chloroquine side effects versus mefloquine Plaquenil for dermatomyositis muscle weakness Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Mar 01, 2011 The American Heart Association is qualified 501c3 tax-exempt organization. *Red Dress ™ DHHS, Go Red ™; AHA; National Wear Red Day ® is registered trademark. Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13 It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil toxicity heart Hydroxychloroquine Plaquenil Toxicity and., Hydroxychloroquine-Induced Cardiomyopathy Circulation. Lyrica and plaquenilHydroxychloroquine and antacids Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. ATLANTA – Hydroxychloroquine Plaquenil 400 mg/day starting by pregnancy week 10 reduces recurrence of congenital heart block in infants born to women with anti-Ro antibodies, according to an open-label, prospective study presented at the annual meeting of the American College of Rheumatology. The American Heart Association is qualified 501c3 tax-exempt organization. *Red Dress ™ DHHS, Go Red ™; AHA; National Wear Red Day ® is registered trademark. Hydroxychloroquine HCQ, a common anti-rheumatic medication, can be cardiotoxic and cause systolic or diastolic heart failure HF. A 65 year old man presented with acute decompensated HF. He had a history of rheumatoid arthritis, and had been treated with hydroxychloroquine for the last 8 years.