Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Buy hydroxychloroquine sulphate Chloroquine lipophilic Photosensitivity reaction is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months, also take medication Humira, and have Pain Rheumatoid Arthritis Medication Beware of Sunburn if You Take These Drugs. A side effect of some RA medicine is sun sensitivity. Be extra careful to avoid skin burns, blistering, and the. The malaria medication hydroxychloroquine Plaquenil may ease the symptoms of some types of sun allergies. Therapy. If you have a severe sun allergy, your doctor might suggest gradually getting your skin used to sunlight each spring. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil sun reaction Sulfasalazine Oral Route Precautions - Mayo Clinic, Rheumatoid Arthritis Medication Beware of Sunburn if You. Lysosomal degradation inhibitor chloroquine I also love the sun, so I would throw on a hat and some 50+ block and just deal with it, but it isn't nearly as enjoyable. I stopped taking the Plaquenil several months ago and no longer have this reaction in the sun. If you feel okay in the sun, I would suggest slathering on the sunscreen, put on a hat and soak it in! Plaquenil and the sun - Sarcoidosis - Inspire. Sun allergy - Diagnosis and treatment - Mayo Clinic. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. In a phototoxic reaction, drug molecules absorb the energy of a specific UV wavelength, which causes the molecule to undergo a chemical change and emit energy that damages surrounding tissues. The reaction is often immediate. It usually occurs after the first dose of a drug and within 24 hours of taking the drug and exposure to the sun. That's a real common side effect of Lupus is unexplained rashes. If you've ever had an allergic reaction to a drug then this is the type of reaction you'd have if you were allergic to the Plaquenil; and they'd stay until the Plaquenil was out of your system. If they're coming and going more than likely it isn't the Plaquenil. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth.