Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine usmle Hydroxychloroquine cure headaches Methotrexate may take longer to become effective, but USUALLY, it will take effective within the time frame you're looking at. It took me 6 months to get efficacy settled, and others longer. Take some time to search both drugs, to get a feel for what you're dealing with. This study is created by eHealthMe based on reports of 23,242 people who take Methotrexate and Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 15 million FDA reports. The results are personalized to your gender and age. Does anyone know if hydroxychloroquine and methotrexate can cause weight loss day, been taking for over a year now but although it helps with some of the pain. I have to have steroid. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Can you take hydroxychloroquine with methotrexate Plaquenil Oral Interactions with Other Medication, Methotrexate and Plaquenil drug interactions - eHealthMe Plaquenil severe rashPlaquenil and cataract surgeryHydroxychloroquine interactions with famotidineHydroxychloroquine sulfate more likely to get sickLysosomotropic agent chloroquine which Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. If you have lupus, it may also improve the rash. It may be as long as 12 weeks before you notice the benefits. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Hydroxychloroquine Side-effects, uses, time to work. Does anyone take methotrexate and hydroxychloroquine.. Hydroxychloroquine MedlinePlus Drug Information. If taking more than 15 mg of MTX orally once a week isn’t working well for you, your doctor might recommend you try methotrexate injections or with splitting the oral dose into two doses over a 12-hour period. The potential side effects would be the same regardless of which form of methotrexate you take. 4. Hydroxychloroquine is sometimes combined with methotrexate for additive benefits for signs and symptoms or as part of a regimen of “triple therapy” with methotrexate and sulfasalazine. Mechanism The mechanism of action of antimalarials in the treatment of patients with rheumatoid arthritis is unknown but is thought to involve changes in antigen presentation or effects on the innate immune system. Taking Folic Acid with Methotrexate for Arthritis 9 Things You Must Know This supplement can help minimize many bothersome side effects from MTX. Methotrexate is the leading disease-modifying anti-rheumatic drug DMARD given to people with rheumatoid arthritis RA and many other types of inflammatory arthritis.